Genetics and Genomics of Gestational Trophoblastic Disease
This article focuses on hydatidiform mole (HM), which is the most common form of gestational trophoblastic disease and the most studied at the genomic and genetic levels. We summarize current laboratory methods to diagnose HM, discuss their limitations and advantages, and share the lessons we have learned. We also provide an overview of the history of recurrent HM, their known genetic etiologies, and the mechanisms of their formation.
Authors
Funding
Canadian Institutes of Health Research Grant PJT 180509Canadian Institutes of Health Research Grant OGB 177939Canadian Institutes of Health Research Grant MOP 86546Canadian Institutes of Health Research Grant 155998Canadian Institutes of Health Research Grant CCI 125687Canadian Institutes of Health Research Grant 102469Canadian Institutes of Health Research Grant 67179Canadian Institutes of Health Research Grant 130364Mitacs Funding