Conduite à tenir devant une femme ayant une cytologie cervico-utérine anormale : actualisation des recommandations INCa après la mise en place du dépistage par le test HPV

Jean-Luc Brun & Xavier Carcopino et al.

To update the recommendations issued by the National Cancer Institute (INCa) on the management of women with abnormal cervical cytology. INCa recommendations on the management of women with abnormal cervical cytology were published in 2016. In 2019, the High Authority of Health (HAS) recommends HPV test for cervical cancer screening in women over 30. It was therefore necessary to update the initial management and follow-up of women with a reflex cytology abnormality after a positive HPV test. We used the modified Delphi method. Each decision tree was modified by the 3 members of the organizing committee and then presented to 35 experts over 2 rounds, in order to obtain their agreement in terms of validity and clarity. This formalized consensus of experts allowed the creation of 17 decision trees instead of 15 previously: 13 on the diagnostic management of abnormal cytology, stratified according to age, and 4 on therapeutic indications in abnormal histology. The median agreement scores were 89% (81-97). These 17 decision trees respond to the different situations that health professionals may encounter in order to enable them to act, to follow-up or delegate according to their specialties.
Authors
Jean-Luc Brun, Christine Bergeron, Gerlinde Averous, Katty Ardaens, Olivier Aynaud, Hortense Baffet, Sylvain Bouquet, Geoffroy Canlorbe, Charlotte Charpentier, Christine Clavel, Béatrix Cochand-Priollet, Monique Courtade, Mélanie Frigenza, Isabelle Garrigue, Jean Gondry, Isabelle Hernandez, Raphaël Hocquemiller, Bernard Huynh, Philippe Judlin, Karine Le Bail-Carval, Lise Lecointre, Jean Leveque, Julia Maruani, Jean-Luc Mergui, Stéphanie Mignot, Joseph Monsonego, Françoise Mousteou, Christopher Payan, Sabine Paysant, Hélène Piclet, Anne-Gaëlle Pourcelot, Jean-Luc Pretet, Patrick Raulic, Pia de Reilhac, Didier Riethmuller, Nadia Thomas, Ariane Weyl, Xavier Carcopino