Long-term outcomes of PARP inhibitors in ovarian cancer: survival, adverse events, and post-progression insights

· 2024-11-13

24Citations
3Influential
Poly-ADP-ribose polymerase inhibitors (PARPis) have revolutionized the management of BRCA-mutated (BRCA
Journal
ESMO Open
TL;DR

The long-term follow-up results from phase III trials in pretreated OC patients are discussed, which led to the Food and Drug Administration’s withdrawal of PARPi indications in this setting.

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