WEE1 inhibition in cancer therapy: Mechanisms, synergies, preclinical insights, and clinical trials

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Zheng Chen

doi:10.1016/j.critrevonc.2025.104710

WEE1 inhibition in cancer therapy: Mechanisms, synergies, preclinical insights, and clinical trials

Zheng Chen · 2025-04-03

11Citations

1Influential

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Critical Reviews in Oncology/Hematology

TL;DR

Insight is provided into optimizing WEE1-targeted therapies and guiding future research to maximize their clinical impact in cancer treatment, to provide insights into acquired resistance, toxicity, and patient selection.

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WEE1 inhibition in cancer therapy: Mechanisms, synergies, preclinical insights, and clinical trials

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