Does dual-energy CT differentiate benign and malignant ovarian tumours?

S.B. Elsherif & P.R. Bhosale et al. · 2020-04-04

To assess the ability of dual-energy computed tomography (DECT) to distinguish benign from malignant ovarian tumours (OTs). Following approval of the institutional review board, the institutional database was mined for treatment-naive patients who underwent primary cytoreduction for OT. Thirty-seven patients were included and divided into those with benign OTs (n = 11) and malignant OTs (n = 26), including high-grade (n = 20) and low-grade (n = 6) malignant OTs. Advanced processing and region of interest delineation on the ovarian mass were performed using the preoperative staging DECT examination using the Advantage Workstation. The pixel-level data of the CT attenuation values at 50, 70, and 120 keV and the effective atomic number (Z Malignant OTs had significantly higher Z DECT may be a tool to help distinguish malignant and benign OTs and predict tumour grade.
Authors
S.B. Elsherif, S. Zheng, D. Ganeshan, R. Iyer, W. Wei, P.R. Bhosale
Funding
Cancer Center Support Grant

National Institutes of Health

P30 CA016672