Mesoporous silica-coated gold nanorod grafted with cisplatin prodrug on the surface enhances radiotherapy for cervical cancer via triple-strategy approach

Jing Wang · 2025-09-25

Concurrent radio-chemotherapy remains the standard treatment for cervical cancer, but its efficacy is limited by tumor hypoxia and enhanced DNA repair in cancer cells. To address these issues, mesoporous silica (MSN)-coated gold nanorod (Au NR) grafted with cisplatin prodrug (MDDP) on the surface and O