Ruthenium(II)-curcumin liposome nanoparticles: Synthesis, characterization, and their effects against cervical cancer

Buddolla Anantha Lakshmi & Sanghyo Kim et al. · 2021-04-19

Ruthenium complexes have increased the scope for improvement in current cancer treatment by replacing platinum-based drugs. However, to reduce metal-associated toxicity, a biocompatible flavonoid, such as curcumin, is indispensable, as it offers uncompensated therapeutic benefits through formation of complexes. In this study, we synthesized metal-based flavonoid complexes using ruthenium(II) and curcumin by adopting a convenient reflux reaction, represented as Ru-Cur complexes. These complexes were thoroughly characterized using
Authors
Buddolla Anantha Lakshmi, Ankireddy Seshadri Reddy, Roopkumar Sangubotla, Jong Wook Hong, Sanghyo Kim