FTO triggers NLRP3/GSDMD-dependent pyroptosis to enhance cisplatin-sensitivity in ovarian cancer

Fubin Zhang & Yutao Guan et al. · 2025-02-23

Chemotherapy resistance is still the major impediment to poor prognosis of ovarian cancer (OC). The fat mass and obesity associated protein (FTO), as the first recognized RNA N6-methyladenosine (m
Links
DOIPubMed
Journal
Cellular Signalling
Authors
Fubin Zhang, Tianhong Zhu, Lei Gan, Yongming Du, Lixiao Liu, Huiqing Ding, Xueqin Chen, Yutao Guan
Funding
Science and Technology Innovation 2025 Major Project of Ningbo Municipality Grant 2022Z148Natural Science Foundation of Ningbo Municipality Grant 2024J371Zhejiang Medical Association Funding