VERU-111 suppresses tumor growth and metastatic phenotypes of cervical cancer cells through the activation of p53 signaling pathway

Q: How does OCRA curate its research paper database?

OCRA indexes peer-reviewed papers from PubMed and CrossRef, enriched with MeSH terms, author profiles, and citation metrics. Papers are categorized by cancer type, research method, and clinical relevance.

Q: Can I search papers by MeSH term or author?

Yes. Use the search bar to filter papers by MeSH term, author name, journal, keyword, or cancer type. Each paper includes linked MeSH terms and author profiles for further exploration.

Q: How current is the paper database?

The database is updated regularly through automated ingestion from PubMed and CrossRef. Most papers appear within days of their PubMed indexing date.

doi:10.1016/j.canlet.2019.11.035

VERU-111 suppresses tumor growth and metastatic phenotypes of cervical cancer cells through the activation of p53 signaling pathway

Vivek K. Kashyap & Subhash C. Chauhan et al. · 2019-12-03

In this study, we investigated the therapeutic efficacy of VERU-111 in vitro and in vivo model systems of cervical cancer. VERU-111 treatment inhibited cell proliferation and, clonogenic potential, induce accumulation of p53 and down regulated the expression of HPV E6/E7 expression in cervical cancer cells. In addition, VERU-111 treatment also decreased the phosphorylation of Jak2

Links

DOI PubMed

Journal

Cancer Letters

Authors

Vivek K. Kashyap, Nirnoy Dan, Neeraj Chauhan, Qinghui Wang, Saini Setua, Prashanth K.B. Nagesh, Shabnam Malik, Vivek Batra, Murali M. Yallapu, Duane D. Miller, Wei Li, Bilal B. Hafeez, Meena Jaggi, Subhash C. Chauhan

Funding

Targeted Nanotherapy for Pancreatic Cancer Targeting the colchicine binding site in tubulin for cancer therapy Development of Targeted Nanotechnology Platform for Pancreatic Cancer Acquisition of a Q-TOF Mass Spectrometer Acquisition of a 400MHz Solution NMR System with an Autosampler Etiology of cervical cancer health disparity in American Indian women MUC13 Mucin in Colerectal Cancer Health Disparity National Institutes of Health Funding

NCI NIH HHS

R01 CA210192

NCI NIH HHS

R01 CA148706

NCI NIH HHS

R01 CA206069

NIH HHS

S10 OD010678

NCRR NIH HHS

S10 RR026377

NCI NIH HHS

U01 CA162106

NCI NIH HHS

R01 CA204552