Clinical implications of incorporating genetic and non-genetic risk factors in CanRisk-based breast cancer risk prediction

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doi:10.1016/j.breast.2023.103615

Clinical implications of incorporating genetic and non-genetic risk factors in CanRisk-based breast cancer risk prediction

Anja Tüchler & Eric Hahnen et al. · 2023-11-29

15Citations

Links

DOI PubMed

Journal

The Breast

TL;DR

Combined consideration of eLTRs and e10YRs allows personalizing IBS starting age and identified BRCA1/2 PV carriers benefitting from IBS <30 years, and women tested non-informative/negative for whom IBS may be postponed.

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Authors

Anja Tüchler, Antoine De Pauw, Corinna Ernst, Amélie Anota, Inge M.M. Lakeman, Julia Dick, Nienke van der Stoep, Christi J. van Asperen, Monika Maringa, Natalie Herold, Britta Blümcke, Robert Remy, Anke Westerhoff, Denise J. Stommel-Jenner, Eléonore Frouin, Lisa Richters, Lisa Golmard, Nadine Kütting, Chrystelle Colas, Barbara Wappenschmidt, Kerstin Rhiem, Peter Devilee, Dominique Stoppa-Lyonnet, Rita K. Schmutzler, Eric Hahnen

Funding

Horizon 2020 Grant 634935 Bundesministerium für Bildung und Forschung (BMBF) Grant 01GY1901 Deutsche Krebshilfe (German Cancer Aid) Grant 110837 Deutsche Krebshilfe Grant 70114178 Horizon 2020 Funding Universität zu Köln Funding Federal Ministry of Education and Research Berlin Office Funding University Hospital Cologne Funding