CRISPR/Cas14a integrated with DNA walker based on magnetic self-assembly for human papillomavirus type 16 oncoprotein E7 ultrasensitive detection

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doi:10.1016/j.bios.2025.117135

CRISPR/Cas14a integrated with DNA walker based on magnetic self-assembly for human papillomavirus type 16 oncoprotein E7 ultrasensitive detection

Yao Yue & Ruijiang Liu et al. · 2025-01-04

To enhance the biomarker diagnostics sensitivity and selectivity of human papillomavirus type 16 oncoprotein E7 (HPV16 E7) in serum, a label/enzyme-free electrochemical detection platform was developed. This platform featured a type of "Super-turn-off" nanobiosensor monitored through differential pulse voltammetry (DPV). It integrated the magnetic self-assembly property of the α-Fe

Links

DOI PubMed

Journal

Biosensors and Bioelectronics

Authors

Yao Yue, Min Liu, Mingyi Ma, Zhihao Xu, Haoda Zhang, Qingxiang Wang, Ruijiang Liu