CCL2 overexpression is associated with paclitaxel resistance in ovarian cancer cells via autocrine signaling and macrophage recruitment

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doi:10.1016/j.biopha.2022.113474

CCL2 overexpression is associated with paclitaxel resistance in ovarian cancer cells via autocrine signaling and macrophage recruitment

Yeong-In Yang & Jung-Hye Choi et al. · 2022-07-30

Tumor cells can secret various cytokines and chemokines, which affect the tumor cells themselves and the neighboring cells. Here, we observed that human ovarian cancer (OC) cells developed resistance to paclitaxel treatment following culture with the conditioned medium (CM) derived from paclitaxel-resistant OC (OC

Links

DOI PubMed

Journal

Biomedicine & Pharmacotherapy

Authors

Yeong-In Yang, Yi-Yue Wang, Ji-Hye Ahn, Bo-Hyung Kim, Jung-Hye Choi

Funding

National Research Foundation of Korea Grant 2017R1A5A2014768 National Research Foundation of Korea Grant 2019R1A2C2011213 National Research Foundation of Korea Grant 2022R1A2C1003498