ClC-3 promotes paclitaxel resistance via modulating tubulins polymerization in ovarian cancer cells

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doi:10.1016/j.biopha.2021.111407

ClC-3 promotes paclitaxel resistance via modulating tubulins polymerization in ovarian cancer cells

Jiezhu Feng & Haifeng Yang et al. · 2021-03-23

Epithelial ovarian cancers (EOC) present as malignant tumors with high mortality in the female reproductive system diseases. Acquired resistance to paclitaxel (PTX), one of the first-line treatment of EOC, remains a therapeutic challenge. ClC-3, a member of the voltage-gated Cl

Links

DOI PubMed

Journal

Biomedicine & Pharmacotherapy

Authors

Jiezhu Feng, Zihan Peng, Lvfen Gao, Xiurou Yang, Zele Sun, Xiuying Hou, Enze Li, Linyan Zhu, Haifeng Yang

Funding

National Natural Science Foundation of China Funding