Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide

Peng Liu & Jinyao Li et al. · 2024-07-31

Ergosterol peroxide (EP) isolated from the edible medicinal fungus Pleurotus ferulae has a wide range of anti-tumor activity, but poor water solubility and low bioavailability limit further application. In this study, EP was structurally modified using triphenylphosphine (TPP
Authors
Peng Liu, Yuhao Yang, Zhe Zhou, Ximeng Zhang, Xuelian Liu, Jinyao Li