Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide
Peng Liu & Jinyao Li et al. · 2024-07-31
Ergosterol peroxide (EP) isolated from the edible medicinal fungus Pleurotus ferulae has a wide range of anti-tumor activity, but poor water solubility and low bioavailability limit further application. In this study, EP was structurally modified using triphenylphosphine (TPP