ATM kinase phosphorylates HSP90 on T297 changing its conformation dynamics and promoting its interaction with HER2 receptor tyrosine kinase

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doi:10.1016/j.bbamcr.2026.120110

ATM kinase phosphorylates HSP90 on T297 changing its conformation dynamics and promoting its interaction with HER2 receptor tyrosine kinase

Giulia Fianco & Daniela Barilà et al. · 2026-01-09

Links

DOI PubMed

Journal

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Authors

Giulia Fianco, Irene Taddei, Veronica Oropallo, Claudia Contadini, Alessandra Ferri, Laura Coculo, Stefano A. Serapian, Giorgio Colombo, Venturina Stagni, Daniela Barilà

Funding

Ministero dell’Istruzione, dell’Università e della Ricerca Grant IG2023-n.27139 Associazione Italiana per la Ricerca sul Cancro Grant 26230 AIRC Italian Association for Cancer Research Funding Ministero dell'Istruzione dell'Universita e della Ricerca Grant PRIN202224M22R European Commission Grant CUP B53D23015820006 European Commission Grant PRIN202224M22R Ministero dell'Università e della Ricerca Funding Consiglio Nazionale delle Ricerche Funding Center for Neuroscience Research Grant DSB.AD006.371-InvAt-FOE2022 Ministry of Health Grant RF-2016-02362022