Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death

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doi:10.1016/j.bbadis.2020.165795

Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death

Julia Yago-Ibáñez & Ana B. Fernández-Martínez et al. · 2020-04-08

Cisplatin's toxicity in renal tubular epithelial cells limits the therapeutic efficacy of this antineoplastic drug. In cultured human proximal tubular HK-2 cells (PTC) a prostaglandin uptake transporter (PGT)-dependent increase in intracellular prostaglandin E

Links

DOI PubMed

Journal

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Authors

Julia Yago-Ibáñez, Coral García-Pastor, Francisco J. Lucio-Cazaña, Ana B. Fernández-Martínez

Funding

Universidad de Alcalá Funding Comunidad de Madrid Funding Universidad Autónoma de Madrid Funding