RAD51 and PALB2 in precision oncology: Clinical implications for HRD associated breast and ovarian cancers (Review)

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doi:10.3892/ijo.2025.5771

RAD51 and PALB2 in precision oncology: Clinical implications for HRD associated breast and ovarian cancers (Review)

Mohd Kausar & Saumyatika Gantayat et al. · 2025-07-04

Maintaining genomic stability is essential for reducing the risk of carcinogenesis. Homologous recombination (HR) is a high‑fidelity DNA repair mechanism that addresses double‑strand breaks and interstrand crosslinks. The present review examined two key components of HR:

Links

DOI PubMed

Journal

International Journal of Oncology

Authors

Mohd Kausar, Khalid Alshammari, Fahaad Alenazi, Sadaf Anwar, Amany Khalifa, Tarig Ginawi, Abdulaziz Asiri, Mohammad Najm, Syed Rabbani, Mohamed El‑Tanani, Saumyatika Gantayat