Calcium signals and potential therapy targets in ovarian cancer (Review)

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doi:10.3892/ijo.2023.5573

Calcium signals and potential therapy targets in ovarian cancer (Review)

Fengying Deng & Qinqin Gao et al. · 2023-09-15

7Citations

Ovarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca

Links

DOI PubMed

Journal

International Journal of Oncology

TL;DR

The potential of Ca2+ signaling as a novel target for the development of effective treatment strategies for OC was discussed and the main roles of ion channel/receptor/pump-triggered Ca2- signaling pathways located at the plasma membrane and organelle Ca2+.

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Authors

Fengying Deng, Mengyu Fu, Chenxuan Zhao, Jiahui Lei, Ting Xu, Bingyu Ji, Hongmei Ding, Yueming Zhang, Jie Chen, Junlan Qiu, Qinqin Gao