IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation

Liu Xu & Yihao Tian et al. · 2020-09-16

Previous studies have demonstrated that the antitumor potential of IU1 (a pharmacological compound), which was mediated by selective inhibition of proteasome-associated deubiquitinase ubiquitin-specific protease 14 (USP14). However, the underlying molecular mechanisms remain elusive. It has been well established that
Authors
Liu Xu, Jing Wang, Xiaoning Yuan, Shuhua Yang, Xiaolong Xu, Kai Li, Yanqi He, Lei Wei, Jingwei Zhang, Yihao Tian