IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation
Liu Xu & Yihao Tian et al. · 2020-09-16
Previous studies have demonstrated that the antitumor potential of IU1 (a pharmacological compound), which was mediated by selective inhibition of proteasome-associated deubiquitinase ubiquitin-specific protease 14 (USP14). However, the underlying molecular mechanisms remain elusive. It has been well established that