HPV vaccination: analysis of acceptability among mothers – a study of 160 cases
Abstract
Objectives
To assess Tunisian mothers’ knowledge, attitudes, and perceptions regarding HPV vaccination, in order to better understand the factors influencing their acceptance.
Methods
A multicenter, cross-sectional analytical study was conducted between December 2024 and January 2025 among 160 mothers residing in Tunisia, each with at least one daughter aged 10–12 years. Data were collected using an anonymous self-administered questionnaire covering socio-demographic information, knowledge of cancer, HPV, and vaccination, as well as attitudes and factors influencing acceptability.
Results
Almost all participants (99.4 %) had heard of cervical cancer, but only 16.3 % were aware of HPV. Knowledge about the HPV vaccine was low (13.1 %). More than half (59.4 %) expressed concerns about side effects. Acceptance of the vaccine was low, with only 21.9 % expressing favorable opinions and 57.5 % unfavorable. In univariate analysis, a higher level of education and knowledge of HPV were associated with a favorable attitude; however, no independent predictors were identified in the multivariate analysis.
Conclusions
This study reveals a low level of knowledge and acceptance of HPV vaccination among Tunisian mothers, mainly due to insufficient information and safety concerns. Culturally adapted educational campaigns and active involvement of healthcare professionals are essential to improve vaccination coverage.