Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites

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Naviya Schuster-Little; Rebecca J. Whelan

doi:10.1039/d0an01701a

Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites

Naviya Schuster-Little & Rebecca J. Whelan

<p>Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) is a desirable goal, because it may enable detection of proteoforms that are analytically silent in the current immunoassay.</p>

NCI NIH HHS

P30 CA014520

NIGMS NIH HHS

T32 GM075762

National Institute of General Medical Sciences

T32GM075762

Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites

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