Large Cell Neuroendocrine Carcinoma of the Uterine Cervix With a Biphasic Synaptophysin Staining Pattern and Followed Vaginal Intraepithelial Recurrence: A Case Report
This case highlights the importance of early, aggressive surgery for large cell neuroendocrine carcinoma and continuous cytological monitoring in detecting recurrence at the early intraepithelial stage. The pagetoid spread pattern with a biphasic synaptophysin staining differentiated LCNEC from CIN3 and AIS.