Efficacy and Safety of Multivisceral Resection for Ovarian Cancer: A Comparative Study of Gynecologic Oncologists and Multidisciplinary Surgeons
ABSTRACT
Background
Advanced ovarian cancer often presents with extensive pelvic and abdominal metastases, even malignant pleural effusion. Consequently, multivisceral resection has become the common surgical approach to achieve optimal resection of ovarian cancer. The present study aimed to evaluate postoperative complications and prognosis of multivisceral resection performed by the independent gynecologic oncologist team (GOT) or multidisciplinary team (MDT).
Methods
The retrospective cohort study enrolled ovarian cancer patients who underwent surgery with multivisceral resection in Jiangsu Cancer Hospital. Patients were divided into two groups depending on the surgical team: the GOT and MDT groups. Patient baseline characteristics, surgical outcomes, postoperative complications, and long‐term prognosis were compared between the GOT and MDT groups.
Results
Between January 2017 and June 2024, 299 ovarian cancer patients were included in this study: 83 in the GOT and 216 in the MDT group. The GOT group had shorter operating times (235 vs. 290 min; p < 0.001) and less blood loss (400 vs. 600 mL; p < 0.001) compared with the MDT group. There were no significant differences in postoperative complications and median progression‐free survival (PFS) (not reached (NR) vs. 22.8 months; HR = 0.818, 95% CI 0.507–1.320; p = 0.410) between the GOT and MDT groups. In multivariate analysis, HRD positive status was an indicator of a favorable prognosis (HR = 0.453; 95% CI 0.243–0.844; p = 0.013).
Conclusion
The results suggest that ovarian cancer patients who underwent multivisceral resection performed by the independent gynecologic oncologist team are safe and feasible. Our team will continue to follow up to obtain more comprehensive survival data to validate this finding.