Low-Grade Endometrial Stromal Sarcoma Diagnosed 8 Years After Hysterectomy With Morcellation

Awa Sanneh & Anna L. Beavis et al.

BACKGROUND:

Morcellation at the time of minimally invasive hysterectomy or myomectomy for presumed benign indications carries a risk of disseminating undiagnosed uterine malignancies.

CASE:

A 57-year-old woman with a remote history of laparoscopic hysterectomy with morcellation of a cellular leiomyoma presented with a newly diagnosed complex pelvic mass. Owing to adherence of the mass to the rectum and numerous peritoneal tumor implants, a surgical cytoreductive procedure was performed. The pelvic mass, implants, and original hysterectomy specimen were histologically identical and consistent with low-grade endometrial stromal sarcoma. Owing to lack of tumor–myometrial interface on the original morcellated specimen, this malignant diagnosis was not made at the time of hysterectomy.

CONCLUSION:

Morcellation of the uterus can hinder an accurate pathologic diagnosis of uterine stromal neoplasms.

Authors
Awa Sanneh, Tricia Murdock, Stephanie L. Wethington, Amanda N. Fader, Deyin Xing, Anna L. Beavis