ALDH2 promotes uterine corpus endometrial carcinoma proliferation and construction of clinical survival prognostic model

Yun-Qian Cui & Xing-Hua Liao et al. · 2021-10-20

UCEC is one of the three common malignant tumors of the female reproductive tract. According to reports, the cure rate of early UCEC can reach 95%. Therefore, the development of prognostic markers will help UCEC patients to find the disease earlier and develop treatment earlier. The ALDH family was first discovered to be the essential gene of the ethanol metabolism pathway in the body. Recent studies have shown that ALDH can participate in the regulation of cancer. In our research, we explored the expression of the ALDH family in 33 cancers. It was found that ALDH2 was abnormally expressed in UCEC. Besides,
Journal
Aging
Authors
Yun-Qian Cui, Yuan Xiang, Fei Meng, Chun-Hui Ji, Rui Xiao, Jia-Peng Li, Zhou-Tong Dai, Xing-Hua Liao