Noncontact Environmental Radiation Sensitization via Photoresponse Processes Mediated by Nanostructured Ru-Based Photosensitizers with Near-Infrared Responsiveness
Ovarian cancer is notorious for peritoneal dissemination and chemoresistance caused by its REDOX homeostasis. Ruthenium-based photosensitizers that destroy the REDOX homeostasis in tumor cells by oxidizing NADH and generating ROS can respond only to blue-green light with poor tissue penetration, thus limiting further clinical applications. Thus, a Ru-based nanoplatform (MR@Au) integrating Mn structural sites and