Activation of Ibuprofen via Ultrasonic Complexation with Silver in N-Doped Oxidized Graphene Nanoparticles for Microwave Chemotherapy of Cervix Tumor Tissues

Darya V. Radziuk · 2022-12-06

4Citations
An ultrasonic method (20 kHz) is introduced to activate pristine ibuprofen organic molecular crystals via complexation with silver in nitrogen-doped oxidized graphene nanoplatforms (∼50 nm). Ultrasonic complexation occurs in a single-step procedure through the binding of the carboxylic groups with Ag and H-bond formation, involving noncovalent π
Links
DOIPubMed
Journal
ACS Biomaterials Science & Engineering
TL;DR

Ibu-Ag-NrGO≫ NPs develop ∼105 order higher changes of the electric field strength intensity than free ibuprofen in the microwave absorption range of 100-1000 MHz as revealed from the theoretical modeling of a cervix tumor tissue.

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Institutions
Belarusian State University Of Informatics And Radioelectronics
Authors
Darya V. Radziuk
Funding
Belarusian Republican Foundation for Fundamental Research Grant B20SLKG-002Belarusian Republican Foundation for Fundamental Research Grant B21KORG-001Belarusian Republican Foundation for Fundamental Research Grant B21M-001Belarusian Republican Foundation for Fundamental Research Grant B21RM-045Belarusian Republican Foundation for Fundamental Research Grant B21TUB-001Belarusian Republican Foundation for Fundamental Research Grant F22Y-007Belarusian State Research Grant 21-3051 57 031.00Belarusian State Research Grant 21-3067 1.17Belarusian State Research Grant 21-3163M