In Situ Construction of Upconverting Nano-Bacteria Biohybrids via Biomimetic Mineralization for Synergistic Antitumor Phototherapy
Nano-bacteria biohybrids, which combine the advantages of nanomaterials and bacterial cells, have emerged as innovative platforms for cancer treatment. Integrated with optical nanomaterials, these biohybrids enable effective phototherapy. To overcome the challenge of limited tissue penetration by visible light in phototherapy, upconversion nanoparticles can be used to convert near-infrared (NIR) light into visible light, enabling the treatment of deep-seated tumors. In this study, we present a rapid method to fabricate upconversion nanoparticle-bacteria biohybrids (