Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models

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Monica A. Haughan; Manead Khin; Zeinab Y. Al Subeh; Yu Gao; Leslie N. Aldrich; Joanna E. Burdette

doi:10.1021/acs.jnatprod.3c00186

Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models

Monica A. Haughan & Joanna E. Burdette et al. · 2023-08-29

High-grade serous ovarian cancer (HGSOC) is the most common and lethal ovarian cancer histotype. Lack of early detection methods, limited therapeutic agents, and low 5-year survival rate reflect the urgent need to develop new therapies. Eupenifeldin, a bistropolone, originally isolated from

Funding

NCI NIH HHS

P01 CA125066

NCI NIH HHS

R35 CA209896

NCCIH NIH HHS

T32 AT007533

NCCIH NIH HHS

T32 AT008938

U.S. Department of Health and Human Services

P01 CA125066

U.S. Department of Health and Human Services

R35 CA209896

U.S. Department of Health and Human Services

T32 AT007533

Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models

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