Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer

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doi:10.3724/abbs.2024111

Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer

Jinrui Sun & Yumei Wu et al.

This study investigates the role of lactate in the genesis and progression of ovarian cancer (OV) and explores the underlying mechanisms. Serum lactate levels show a positive correlation with tumor grade and poor prognosis in patients with OV. Bioinformatics analysis identifies

Links

DOI PubMed

Journal

Acta Biochimica et Biophysica Sinica

Authors

Jinrui Sun, Qinmei Feng, Yue He, Ming Wang, Yumei Wu