Vitamin D receptor (VDR) variants are risk factors for ovarian cancer: a meta-analysis and trial sequential analysis

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Yi Zhang

doi:10.1080/15257770.2024.2302525

Vitamin D receptor (VDR) variants are risk factors for ovarian cancer: a meta-analysis and trial sequential analysis

Yi Zhang · 2024-01-19

2Citations

The importance of Vitamin D in ovarian cancer (OC) has been well documented, and lower levels have been associated with susceptibility to OC. Vitamin D exerts its effect through the vitamin D receptor (VDR). Common genetic variants in the VDR gene (

Links

DOI PubMed

Journal

Nucleosides, Nucleotides & Nucleic Acids

TL;DR

A meta-analysis of VDR FokI and BamI variants revealed a significant association with an increased risk of OC, and highlighted the requirement for additional case-control studies in VDR (ApaI, BamI and TaqI) to draw a definitive conclusion.

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Institutions

Chinese Academy Of Sciences

Authors

Yi Zhang