Moving Beyond BRCA—Incorporating Molecular Assays into Ovarian Cancer Trials

Q: How does OCRA curate its research paper database?

OCRA indexes peer-reviewed papers from PubMed and CrossRef, enriched with MeSH terms, author profiles, and citation metrics. Papers are categorized by cancer type, research method, and clinical relevance.

Q: Can I search papers by MeSH term or author?

Yes. Use the search bar to filter papers by MeSH term, author name, journal, keyword, or cancer type. Each paper includes linked MeSH terms and author profiles for further exploration.

Q: How current is the paper database?

The database is updated regularly through automated ingestion from PubMed and CrossRef. Most papers appear within days of their PubMed indexing date.

doi:10.1158/1078-0432.CCR-20-2429

Moving Beyond BRCA—Incorporating Molecular Assays into Ovarian Cancer Trials

Michelle McMullen & Amit M. Oza et al. · 2020-08-14

Abstract

PrOTYPE is a locked down assay validated to Institute of Medicine standards, using NanoString technology to classify high-grade serous ovarian cancer into four defined subgroups. Future directions will include prospective–retrospective analysis and prospective clinical validation to define the predictive role of this assay and its role in influencing treatment decisions.

See related article by Talhouk et al., p. 5411

Links

DOI PubMed

Journal

Clinical Cancer Research

Authors

Michelle McMullen, Katherine Karakasis, Amit M. Oza

Funding

Ontario Institute for Cancer Research Funding Government of Ontario Funding