Clinical Validation of DNA Methylation Detection in Cervical Exfoliated Cells for Endometrial Cancer in Women with Suspected Lesions

Yi Yu & Limei Chen et al. · 2026

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TL;DR

DNA methylation detection in exfoliated cervical cells demonstrates high sensitivity and specificity for EC detection, and the combination with TVS further enhances sensitivity and NPV, offering a simple and non-invasive triage strategy for patients with suspected endometrial lesions.

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Authors
Yi Yu, Tingting Su, Hongwei Zhang, Qing Li, Qing Cong, Long Sui, Limei Chen