TL;DR
It is proved that SIRT1 maintains a functional mitochondrial pool through PGC1α and MTP18 for biogenesis and fission of mitochondria during arecoline exposure and could decrease the risk of mitochondria dysfunctionality associated with the onset of oral carcinogenesis.
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Authors
Bishnu Prasad Behera, Soumya Ranjan Mishra, Kewal Kumar Mahapatra, Shankargouda Patil, Thomas Efferth, Sujit Kumar Bhutia
