TL;DR
The analytical challenges implied by secretomics are revisited and an overview of affinity-based proteomic platforms currently available for such analyses are provided, using the study of the tumor secretome as an example for basic and translational research.
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Authors
Vanessa M. Beutgen, Veronika Shinkevich, Johanna Pörschke, Celina Meena, Anna M. Steitz, Elke Pogge von Strandmann, Johannes Graumann, María Gómez-Serrano