Mitochondrial dysfunction mediated by thioredoxin-interacting protein: A crucial determinant in di(2-ethylhexyl) phthalate-induced liver failure.

Peng Xu & Wang Zhang et al. · 2024

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This study supports the hypothesis that DEHP induces mitochondrial oxidative stress through the TXNIP signaling pathway, resulting in liver dysfunction in mice, and suggests possible links between endocrine-disrupting chemicals and human diseases.

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Authors
Peng Xu, Yang-ni Su, Chen Ling, Jing Wang, Wang Zhang