The protective effect of caffeine against oxalate-induced epithelial-mesenchymal transition in renal tubular cells via mitochondrial preservation.

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doi:10.1016/j.biopha.2024.116144

The protective effect of caffeine against oxalate-induced epithelial-mesenchymal transition in renal tubular cells via mitochondrial preservation.

Rattiyaporn Kanlaya & Visith Thongboonkerd et al. · 2024

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TL;DR

The anti-fibrotic mechanism of caffeine during oxalate-induced EMT in renal cells is unveiled by preserving mitochondrial biogenesis and function by preserving mitochondrial biogenesis and function.

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Authors

Rattiyaporn Kanlaya, Chonnicha Subkod, Supanan Nanthawuttiphan, Visith Thongboonkerd