Clinical value of preoperative serum calcium level in predicting deep infiltrative endometriosis among ovarian endometrioma
To evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma. A retrospective, observational cohort study. A total of 2,557 women who underwent surgery for benign ovarian tumors were initially enrolled. Of these, 987 were pathologically confirmed to have endometriosis, while the remaining 1570 did not. Endometriosis (EM) group had significantly lower albumin-adjusted calcium levels than the non-EMs group ( Albumin-adjusted calcium level was lower in patients diagnosed with EM compared to those with other benign ovarian tumors. The combined use of albumin-adjusted calcium and CA125 may potentially offer enhanced diagnostic utility for EM, though further validation is required. Moreover, a lower serum level of albumin-adjusted calcium was associated with the presence of DIE among EM patients.