In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with and without metabolic activation
Although the presence of nitro groups in chemicals can be recognized as structural alerts for mutagenicity and carcinogenicity, nitroaromatic compounds have attracted considerable interest as a class of agents that can serve as source of potential new anticancer agents. In the present study, the