Roles of Beclin1 protein expression in cervical cancer: a meta-analysis and bioinformatics analysis

Guan-Ying Ma & Zhi-Gang Zhang et al. · 2022-07-09

1Citations
Beclin1 is a key regulator of a family of autophagy-related proteins. The aim of our study was to elucidate the clinicopathological and prognostic significance of Beclin1 expression which is a positive regulator of autophagy in cervical cancer. The results showed that a total of 2682 patients were enrolled in 21 case-control studies. The results showed that, as for Beclin1 expression, significant differences were found in cervical cancer vs. normal cervical tissues (
TL;DR

The aim of the study was to elucidate the clinicopathological and prognostic significance of Beclin1 expression which is a positive regulator of autophagy in cervical cancer, and to provide methods and ideas for prevention and treatment.

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Authors
Guan-Ying Ma, Shuai Shi, Hong-Yan Ma, Zhi-Gang Zhang