Journal

European Journal of Oncology Nursing

Papers (25)

Intimate partner violence and its associated psychosocial factors among women with breast and/or cervical cancer in China: A cross-sectional study

This study aimed to investigate the prevalence of intimate partner violence among women with breast cancer and/or cervical cancer in China and to explore its psychosocial associated factors. From July to September 2023, we firstly conducted reliability and validity tests using the simplified Chinese version of the Women Abuse Screening Tool in 150 women with breast and/or cervical cancer. We then used a questionnaire comprising the Chinese version of the Women Abuse Screening Tool, Multidimensional Scale of Perceived Social Support, European Organization for Research and Treatment Quality of Life Questionnaire-Core 30, and Experiences in Close Relationships Inventory Scale in 401 women with breast and/or cervical cancer. The descriptive and inferential statistics were determined using SPSS 26.0 version. The prevalence of intimate partner violence in China among women with breast and/or cervical cancer was 40.9% and 49.00%, respectively. Through logistic regression analysis, we found that current work status, monthly income, diagnosis time, attachment avoidance, and quality of life were factors affecting intimate partner violence in the women with breast and/or cervical cancer. The prevalence of intimate partner violence among women with breast and/or cervical cancer was high in China. Intimate partner violence had a negative impact on social support and quality of life among the study participants, and their attachment patterns were more inclined to attachment avoidance. As medical workers, early intimate partner violence screening and appropriate intervention measures should be undertaken to reduce the impact of intimate partner violence on women with breast and/or cervical cancer.

The impact of frailty on chemotherapy intolerance in patients with cervical cancer: A longitudinal study

To explore the potential effects of frailty on chemotherapy intolerance in patients with cervical cancer. A longitudinal study of patients with cervical cancer undergoing postoperative Adjuvant Chemotherapy (ACT) was conducted at a hospital in Northwest China from July 2020 to December 2021. Baseline frailty was assessed using the Tilburg Frailty Indicator. Chemotherapy intolerance was obtained from electronic medical records during the intervals between each postoperative chemotherapy session. We used Generalized Estimating Equations (GEE) to determine the predictors and cox regression analysis to analyze the impact of frailty on chemotherapy intolerance. A total of 259 patients with postoperative cervical cancer with a mean age of 52.5 years (SD = 10.3) participated in this study. The incidence of chemotherapy intolerance in the frail group at T1, T2, T3 and T4 was 51.6%, 38.9%, 55.6% and 73.7%, respectively. The patients with frailty were more likely to have chemotherapy intolerance (OR = 1.495, 95% CI: 1.074-2.080, P < 0.05), prolonged hospitalizations (OR = 1.577, 95% CI: 1.086-2.291, P < 0.05) and unplanned readmissions (OR = 2.304, 95% CI: 1.387-3.829, P < 0.05) compared to the patients without frailty. Cox regression analysis showed that frailty increased the risk of chemotherapy intolerance by 1.681-fold (HR = 1.681, 95%CI 1.041-2.713; P < 0.05) and unplanned readmissions by 2.812-fold (HR = 2.812, 95%CI 1.521-5.200; P < 0.05). Frailty can lead to an increased risk of chemotherapy intolerance in patients with cervical cancer undergoing postoperative ACT, and patients with frailty are more likely to experience prolonged hospitalizations and unplanned readmissions.

Information needs of women with BRCA mutations regarding cancer risk management and decision-making

Providing women who have tested positive for a pathogenic variant in BRCA1 or BRCA 2 relevant information can help them to make informed decisions about managing their cancer risk. However, there is a lack of targeted informational support for BRCA positive women specific to the Irish context. The objective of this study is to identify the information needs of women diagnosed with a pathogenic variant in BRCA1 or BRCA 2 regarding cancer risk management and decision-making. This is a descriptive qualitative study. Participants were recruited using purposive sampling and included women with a pathogenic variant in BRCA1 or BRCA2 without a history of breast or ovarian cancer. Two focus groups were held with women (n = 16) to enable them to generate ideas and understanding of their shared information needs. In addition, ten individual interviews were conducted to capture the additional perspectives of health care and relevant policy stakeholders. Interviews were analysed using inductive coding (Braun and Clarke, 2006), with NVivo software (Qsr international, 1999). Three main themes were identified, Cancer Risk Management, Receiving Information, and Implications to Health and Wellbeing. BRCA-positive women expressed a need for information about managing their cancer risk. They were particularly concerned with managing the impact of cancer risk-reducing interventions on their psychological and physical health, wellbeing, and family life. Many women felt they had to advocate for themselves to get treatment and receive information. Participants expressed a need for a comprehensive informational resource where all relevant information related to BRCA risk management could be accessed at a single location. This study suggests that women diagnosed with a pathogenic variant in BRCA1 or BRCA2 in Ireland need more accessible information about managing their cancer risk, and the impact of a BRCA diagnosis on their family, health and wellbeing. These results will be used to identify relevant content for developing an informational decision aid for Irish women.

Effects of expressive writing of positive emotions on mental health among patients with ovarian cancer undergoing postoperative chemotherapy

Patients with ovarian cancer often experience significant psychological distress during postoperative chemotherapy, including anxiety and depression. Expressive writing of positive emotions has shown potential in improving psychological health and fostering post-traumatic growth (PTG) in cancer patients. However, its application to ovarian cancer patients undergoing chemotherapy remains under-explored. A quasi-experimental study was conducted with 82 ovarian cancer patients undergoing postoperative chemotherapy at a tertiary hospital in Changchun, China. Patients were divided into an experimental group (n = 40) receiving expressive writing intervention and a control group (n = 42) receiving routine care. Outcomes were assessed using the Post-Traumatic Growth Inventory (PTGI), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) at baseline and after a 6-week intervention. After the intervention, the experimental group exhibited significantly higher PTGI scores (mean ± SD: 73.43 ± 6.95) compared to the control group (63.19 ± 5.91, P < 0.001), with improvements observed across all five PTG dimensions (P < 0.05). The experimental group also showed a greater reduction in SAS (mean ± SD: 38.25 ± 4.31 vs. 45.12 ± 5.17, P < 0.001) and SDS scores (mean ± SD: 42.10 ± 3.86 vs. 48.75 ± 4.62, P < 0.001). Expressive writing of positive emotions significantly enhances PTG and reduces anxiety and depression in ovarian cancer patients undergoing chemotherapy. This intervention offers a cost-effective and feasible approach for psychological support in clinical settings.

Lived time in ovarian cancer – A qualitative phenomenological exploration

To explore lived time of women with ovarian cancer during chemotherapy. Consensual qualitative research combined with descriptive phenomenology on a purposive sample of 9 middle-aged women (aged between 33 and 52 years, mean age 41.7) with ovarian cancer undergoing chemotherapy in an outpatient chemo center in a clinical hospital. Patients partnered in the design of the study by reviewing the research questions. Four essential temporal structures were uncovered, namely: 1) Explicit finitude - the vivid presence of the thoughts of one's limited lifespan and of time passing towards death. 2) Broken horizon - a sense of an overwhelming unpredictability of life that makes one living in the narrow present. 3) The paradoxes of the chemo-clock - treatment rhythm becoming a basis for the conceptualization of time while lived experience both decelerates and accelerates. 4) Happiness closed-off by regret - the past being distantiated yet present in the form of thoughts about actions that have not been accomplished and no longer can. The research shows unsecure lived time of participants, particularly anxiety concerning premature death and fear of the future due to harsh prognosis. The proposed hybrid method of collecting and analyzing data is an example of combining phenomenological and scientific-objectifying procedures. It can lead to wider replications in different populations with respect to type and stage of the cancer and treatment.

The impact of brachytherapy on sexual life in patients with gynecological cancer

This study was conducted to evaluate the effects of brachytherapy on sexual life in patients diagnosed with gynecological cancer and undergoing brachytherapy. This is a descriptive cross-sectional study. The sample consisted of patients who met the inclusion criteria, were diagnosed with cervical or endometrial cancer, applied to the unit for brachytherapy, and were continuing with the treatment. The study was completed with 87 patients who were continuing their treatment during the second assessment and 77 patients during the third assessment. In this study, at the third month, women experienced significantly higher levels of problems such as loss of sexual desire, avoidance of sexual intercourse, pain during intercourse, changes in sexual life due to brachytherapy, inability to achieve orgasm, and lack of sexual approach from their partner (p < 0.05). In assessments conducted with gynecological cancer patients at the 3rd month after brachytherapy, the total scores of the Female Sexual Function Index (FSFI) and the Sexual Satisfaction Scale for Women (SSS-W) were found to be significantly higher compared to the scores obtained before brachytherapy and at the 6th month after brachytherapy (p < 0.05). For gynecological cancer patients undergoing brachytherapy, the implementation of not only short-term but also long-term follow-up and supportive rehabilitation programs is critically important for assessing sexual symptoms and maintaining sexual well-being.

Understanding experiences and improvement needs of Chinese cervical cancer patients with external beam radiotherapy and 3D brachytherapy: A qualitative study using persona-driven journey maps

Cervical cancer patients undergoing 3D external beam radiotherapy plus brachytherapy face significant physical and psychological burdens. This study aimed to explore their experiences across the treatment journey to improve care. Semi-structured interviews and participant observation with 20 Chinese cervical cancer radiotherapy patients gathered data on psychological, behavioral, social support, and needs aspects. Thematic analysis informed the creation of user personas and journey maps. Clinical applicability and accuracy were assessed via questionnaires completed by 60 patients. Patients exhibited substantial physical, psychological, and social needs throughout treatment, with variations across groups and stages. Four distinct treatment stages were defined: initial intervention, external beam radiotherapy, 3D brachytherapy, and long-term follow-up, each with stage-specific and cross-journey needs. Five typical patient profiles were identified and mapped to stage-specific needs. Questionnaire validation confirmed the profiles effectively captured patients' emotional fluctuations and evolving needs across stages. Combining user personas and journey mapping successfully depicted cervical cancer radiotherapy patients' needs and emotional changes across treatment phases, validated for clinical use. This framework provides a basis for personalized interventions to optimize patient experience and outcomes.

Association between psychological flexibility and self-perceived burden in patients with cervical cancer: A computer-simulated network analysis

The study aimed to identify the profiles of psychological flexibility in patients with cervical cancer and how self-perceived burden networked to different psychological flexibility profiles. The Personalized Psychological Flexibility Index and the Self-Perceived Burden for Cancer Patients were used to measure psychological flexibility and self-perceived burden in patients from the "Be Resilient to Cancer" project. Latent profile analysis was used to identify profiles and computer-simulated network analysis was conducted to determine if self-perceived burden networked to any of the psychological flexibility profiles. A total of 325 patients with cervical cancer were recruited in this study. Mean age was 42.26 years, the majority were married (71%) and 75.4% had early stage disease (I or II). Three profiles of psychological flexibility were identified: moderate avoidance-low acceptance/harnessing (34.8%), high avoidance-moderate acceptance/harnessing (36.9%), low avoidance and high acceptance/harnessing (28.3%). Furthermore, "worrying about damaging family relationships" and "feeling guilty about affecting family's life plans" were the most bridge symptoms as well as the targeted intervention symptoms for alleviating and aggravating the self-perceived burden respectively. Three patterns of psychological flexibility were recognized with two symptoms might be targeted to improve the self-perceived burden in women with cervical cancer.

Psychological resilience, dyadic coping, and dyadic adjustment in couples dealing with cervical cancer in Northwest China: A cross-sectional study

To examine the relationship between dyadic coping and dyadic adjustment in patients with cervical cancer and their spouses in northwest China, and explore the mediating role of psychological resilience in this relationship. A cross-sectional study was conducted from June to October 2024 in two tertiary hospitals in Xinjiang Province, China; 260 patients with cervical cancer and their spouses were enrolled. Participants independently completed demographic and clinical questionnaires as well as Chinese versions of the Resilience Scale, Dyadic Coping Inventory, and Locke-Wallace Marital Adjustment Scale. The Actor-Partner Interdependence Model was employed to analyze dyadic data. Patients with cervical cancer and their spouses both exhibited actor effects (β = 0.197, P < 0.001; β = 0.342, P < 0.001) and partner effects (β = 0.276, P < 0.001; β = 0.264, P < 0.001) in the association between dyadic coping and dyadic adjustment. Regarding the mediating role of psychological resilience, spouses' dyadic coping directly affected patients' psychological resilience, and patients' psychological resilience indirectly influenced their own dyadic adjustment (β = 0.061, 95% CI = 0.019, 0.121; β = 0.074, 95% CI = 0.019, 0.144). Our findings suggested that psychological resilience plays an essential role in enhancing dyadic coping and cultivating dyadic adjustment among patients with cervical cancer and their spouses. Healthcare professionals should identify couples who have difficulty coping and adapting, and consider couple-centered dyadic resilience interventions to improve these behaviors.

Predicting lower limb lymphedema after cervical cancer surgery using artificial neural network and decision tree models

This study aimed to develop and validate accessible artificial neural network and decision tree models to predict the risk of lower limb lymphedema after cervical cancer surgery. We selected 759 patients who underwent cervical cancer surgery at the Hunan Cancer Hospital from January 2010 to January 2020, collecting demographic, behavioral, clinicopathological, and disease-related data. The artificial neural network and decision tree techniques were used to construct prediction models for lower limb lymphedema after cervical cancer surgery. Then, the models' predictive efficacies were evaluated to select the optimal model using several methods, such as the area under the receiver operating characteristic curve and accuracy, sensitivity, and specificity tests. In the training set, the artificial neural network and decision tree model accuracies for predicting lower limb lymphedema after cervical cancer surgery were 99.80% and 88.14%, and the sensitivities 99.50% and 74.01%, respectively; the specificities were 100% and 95.20%, respectively. The area under the receiver operating characteristic curve was 1.00 for the artificial neural network and 0.92 for the decision tree model. In the test set, the artificial neural network and decision tree models' accuracies were 86.70% and 82.02%, and the sensitivities 65.70% and 67.11%, respectively; the specificities were 96.00% and 89.47%, respectively. Both models had good predictive efficacy for lower limb lymphedema after cervical cancer surgery. However, the predictive performance and stability were superior in the artificial neural network model than in the decision tree model.

Effectiveness of a narrative nursing intervention on reproductive concerns in women of childbearing age undergoing cervical cancer surgery: A randomized controlled trial

This study aims to explore the intervention effects of narrative nursing on the reproductive concerns of cervical cancer patients of childbearing age undergoing surgical treatment. Patients undergoing cervical cancer surgery with moderate to severe levels of reproductive concerns, treated between January and December 2023 at a tertiary Grade-A oncology hospital in China, were selected as the research subjects. Patients were randomized into an intervention group and a control group, each consisting of 33 patients. The control group received standard nursing care, while the intervention group received a narrative nursing intervention in addition to standard care. The changes in the levels of reproductive concerns, post-traumatic growth, and quality of life scores before and after the intervention were compared between the two groups. After the intervention, the reproductive concerns scores of the cervical cancer patients in the intervention group (32.53 ± 4.77) were significantly lower than those in the control group (59.29 ± 3.24), with a statistically significant difference (t = 26.143, p < 0.001). The post-traumatic growth scores in the intervention group (86.78 ± 3.52) were significantly higher than those in the control group (68.06 ± 6.24), with a statistically significant difference (t = -14.595, p < 0.001). The quality of life scores in the intervention group (149.00 [IQR = 8.75]) were significantly higher than those in the control group (129.00 [IQR = 13.00]), with a statistically significant difference (z = -5.799, p < 0.001). Narrative nursing can effectively alleviate reproductive concerns in cervical cancer patients undergoing surgical treatment, promote positive psychological changes post-trauma, and improve patients' quality of life.

Support for an innovative approach to delivering gynaecological cancer nursing guidance: A qualitative exploration – Part 2

Gynaecological cancer nurses in Australia are seeking formal guidance to support them and improve equitable nursing care delivery. No comprehensive guide for specialised nursing care of gynaecological cancers is available; however, it is recognised that challenges exist to guidance implementation and active involvement of stakeholders during development is critical to enhance implementation success. This study aimed to explore expectations of nurses and people with lived experience during development of a guidance resource for specialised gynaecological cancer nursing. This paper presents expectations on content and design. Utilising an exploratory qualitative descriptive design, gynaecological cancer nurses and people with lived experience of a gynaecological cancer participated in focus groups or interviews following a semi-structured interview guide. Transcripts underwent inductive content analysis. Participants included 20 nurses and seven people with lived experience of gynaecological cancers. Two major themes emerged: "Support care and educate nurses with content across the care continuum" and "Design the guidance with functionality and practicality for nurses in everyday practice". Participants wanted provision of "practical and instructive" guidance that "incorporates interactive elements", "ensures easy accessibility" and "integrates visual appeal". "Comprehensive patient support content linked to clinical tools and external resources" and "Including education on disease, nursing roles and well-being" were considered important. Expectations for gynaecological cancer nursing guidance to include content across the care continuum and functionality supports the need to plan for an innovative resource format. Further exploration of implementation determinants, along with adopting an implementation science framework and integrating adult learning principles is recommended.

Evaluation of therapy support through a standardized nursing consultation for patients undergoing oral tumor therapy in gynecological oncology within the prospective CAMPA initiative

The increase of oral tumor therapies (OTT) poses new challenges in patient care. Within CAMPA (Care improvement for advanced or metastatic breast and ovarian cancer patients treated with PARP-inhibitors), additional nursing support for patients treated with PARP-inhibitors was developed. Additional nursing support (1 year) was evaluated in breast and gynecooncological cancer patients at an academic and a non-academic outreach center. From 02/22 to 02/24, quality of life, contacts, adherence, documentation of drug intake, hospitalization, and adverse events were evaluated, using CANKADO-ePRO and validated questionnaires reviewed by the Ethics Committee of Medical Faculty, LMU Munich. Satisfaction with care was recorded from 03/23 to 02/24. Supporting materials and interprofessional checklists were explored. The collective (n = 50) included 41 patients with ovarian, 4 with fallopian tube and 5 with breast cancer. Adherence measured by continuous documentation of medication intake was high among patients (78.0%). Quality of life improved from 68.6% to 81.4%, strongly correlating with decreasing numbers of side effects (p = 0.003) (Spearman |ρ| = 0.93). Satisfaction with care was very high (4.97 out of 5 points). 94.6% agreed that nursing consultation was essential for therapy safety compared to the doctor's consultation alone (p < 0.05). The reduction in time and care effort was significant (p < 0.05), having its maximum within the first three months. Standardized nursing consultation was highly appreciated with an important contribution to adherence and improvement in quality of life. Delegation of therapy management to nurses reduces time effort and increases their responsibility, improving interprofessional care at academic and non-academic institutions. Clinical Trials Registry, LMU university hospital, Germany, Healthcare research project, number: 21-0848.

Benchmarking vulvar cancer wound care practice in Australia and New Zealand: A cross-sectional study

This study aimed to investigate current vulvar cancer wound care practices in Australia and New Zealand, identify knowledge of evidence supporting practice, explore enablers and barriers and determine areas for future improvement and research. An online cross-sectional survey collected quantitative and qualitative data from 64 nurses and doctors between May and July 2023. Descriptive statistics and content analysis were conducted. A consumer advisory group contextualised findings within lived experiences. Common vulvar wound care practices included wound irrigation (n = 48, 83 %) and perineal drying (n = 40, 69 %), along with urinary catheters (n = 50, 86 %) and drains (n = 33, 57 %). Not using a wound dressing was common (n = 41, 71 %). Using silver (n = 25, 39 %), topical (n = 11, 17 %) or prophylactic (n = 2, 3 %) antibacterial agents were less common. Only 23 % (n = 15) of respondents reported knowledge of organisational guidance and care was commonly determined by practitioner preference, clinical assessment, and specialist wound nurse review. Reported enablers included guidance documents, clear instructions, clinician expertise, effective communication, and a well-informed patient. Reported barriers included infection, comorbidities, clinician variability, lack of evidence, systematic barriers, poor communication, and wound access challenges. The most common suggestion for improvement was the development of evidence based guidance. Four priority areas for future research were identified as; building an evidence base, evaluating the patient experience, investigating the impact of reducing risk factors and evaluating education interventions. By benchmarking current wound care practices following surgery for vulvar cancer in Australia and New Zealand, priorities to direct future research and practice change efforts are supported.

Fear of recurrence in women with ovarian cancer: A qualitative evidence synthesis

Approximately 80% of ovarian cancers recur after first-line treatments. Women with ovarian cancer (OC) are therefore particularly vulnerable to experiencing fear of cancer recurrence (FCR). This study aimed to synthesise experiences of fear of cancer recurrence among women living with ovarian cancer. A qualitative evidence synthesis (QES) was conducted in accordance with the Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) guidelines. A systematic search of seven databases was undertaken to identify all available qualitative research exploring fear of cancer recurrence in women with OC. Thematic synthesis of extracted data from included studies was undertaken and managed in NVivo. Twenty-two papers reporting on eighteen studies were included in the synthesis. Three main themes were developed (triggers, responses, and coping) and included ten subthemes. FCR was triggered by factors relating to awareness of prognosis, treatment, and negative communication. Women responded to FCR by performing body checking and protecting their families. FCR led to adverse effects on women's wellbeing as it exacerbated uncertainty about their future. Women attempted to cope with FCR through seeking support, regaining control, and redirecting negative thoughts and actions. Women use a variety of approaches to manage their fear of recurrence. Further research on the most appropriate interventions for FCR tailored specifically to the needs of women with OC is needed.

Coping with fear of cancer recurrence among ovarian cancer survivors living in small urban and rural settings: A qualitative descriptive study

Fear of cancer recurrence (FCR) is a paramount concern among ovarian cancer survivors. Evidence shows that cancer survivors living in regional or rural areas have higher psychological morbidity; however, no known studies have explored how ovarian cancer survivors living in small urban and rural areas cope with FCR. In this qualitative descriptive study, a semi-structured questioning process was developed in accordance with Carver et al.'s conceptualization of coping. Focus groups or 1:1 telephone interviews were used to collect data from a convenience sample of ovarian cancer survivors. Participants completed a demographic form and the Fear of Cancer Recurrence Inventory, and clinical information was extracted from hospital charts. The average age of participants (n = 15) was 62.8 years (Range 51-76 years) and the average time since diagnosis was 2.7 years (Range 1-19 years). Most women had elevated levels of FCR. Five themes for coping were expressed by all women: 1) health care provider support; 2) knowing, trusting, and prioritizing self; 3) finding what works; 4) uniqueness and belonging; and 5) redirecting thoughts and actions. One additional theme was expressed by most women (n = 11): 6) preparing for the future. Fear of cancer recurrence was a concern for most ovarian cancer survivors who used a variety of ways to cope. Results can be used to guide nurses' discussions with post-treatment ovarian cancer survivors or be used to inform refinement and development of resources to assist ovarian cancer survivors living in small urban and rural settings to cope with FCR.

Adaptation and psychometric testing of the Chinese version of the Revised Illness Perception Questionnaire for cervical cancer patients

Illness perception is an important factor that influences psychological distress, coping behaviors, and illness outcomes, and this factor is often assessed by the Revised Illness Perception Questionnaire (IPQ-R). Data regarding illness perception among cervical cancer patients are limited, especially in China. The study aimed to adapt and psychometrically test the Chinese version of the IPQ-R for Cervical Cancer (CIPQ-R-CC). This was a methodological study. Before the survey, the identity and causal subscales (originally 14 and 18 items, respectively) were adapted. Data were collected from 220 cervical cancer patients (N = 220) from June 2018 to February 2019. Psychometric properties were assessed using explanatory factor analysis, confirmatory factor analysis, Pearson correlation coefficients, one-way analysis of variance, t-tests and Cronbach's alpha coefficients. Eight identity items and twenty-six causal items were included in the CIPQ-R-CC, which showed acceptable content validity (I-CVI = 0.78-1.00, S-CVI = 0.97-0.99). A five-factor solution was obtained from the cause subscale by explanatory factor analysis, and these factors explained 60.19% of the total variance. For Part III of the CIPQ-R-CC, after deleting nine items and respecifying five error covariances, the proposed seven-factor model was confirmed. There were low to moderate correlations between the latent factors (r<0.52). Known-group validity was demonstrated in some groups with different demographic characteristics. The Cronbach's alpha coefficients were also acceptable (0.60-0.88). The CIPQ-R-CC is a reliable and valid tool for assessing illness perception among Chinese cervical cancer patients. Future studies are needed to verify its factor structure and to confirm its theoretical connotation.

Posttraumatic growth trajectories of couples with gynecological cancer: A longitudinal study

We aimed to describe and compare posttraumatic growth (PTG) levels among gynecological cancer patients and spouses at various time points within one year of diagnosis, as well as to investigate the association, trajectory, and subgroup characteristics of their PTG. Couples in a longitudinal observational study filled out questionnaires within 1 month of gynecological cancer diagnosis, as well as 3, 6, and 12 months later. A growth mixture model (GMM) was utilized to explore PTG trajectories. Statistical analyses included Spearman rank correlation, chi-square test, nonparametric test, and post-hoc test. A significant positive correlation was found between the PTG scores of patients and spouses at different times (P < 0.01), with the patients' scores being significantly higher (P < 0.001). Within a year of diagnosis, patients' and their spouses' PTG showed an overall upward trend. The GMM identified three categories for patients' PTG trajectories: high stability (33.7%), decline (19.1%), and low growth (47.2%). Similarly, spouses' PTG trajectories fell into three categories: medium growth (42.8%), decline (8.6%), and low stability (48.6%). Subgroup analysis of patients and spouses with different PTG trajectories indicated significant differences concerning educational attainment, residence location, per capita monthly family income, payment method of patients' medical expenses, and subjective severity of patients' diseases (P < 0.05). This study represents the inaugural effort to investigate the levels and correlations of PTG between gynecological cancer patients and their spouses from a longitudinal perspective. Furthermore, three distinct trajectories were identified for both partners. Patients and spouses exhibiting different PTG trajectories possess unique demographic and disease characteristics.

How symptom distress mediates the relationship between individual differences and perceived controllability among women with gynecologic cancer

This study aims to investigate the individual differences in perceived controllability among women with gynecologic cancer who are undergoing chemotherapy. We also examined the mediating effect of symptom distress on the relationship between individual differences and perceived controllability. This cross-sectional study employs purposive sampling; data were collected via self-reported questionnaires. In total, 170 women completed the survey. Structural equation modeling was used to examine the proposed hypotheses of the mediating effect of symptom distress. Results revealed that individual differences in age (r = -0.20, p < .05), education (t = -2.24, p < .05), employment (t = -2.05, p < .05), cancer stage (t = 2.35, p < .05), and number of chemotherapy sessions in the past three months (r = -0.16, p < .05) were significantly associated with perceived treatment control. Physical, but not psychological, symptom distress fully mediated the relationship between individual differences and perceived controllability. Participants who perceived financial distress (β = 0.179, p < .05) and those who had undergone a higher number of chemotherapy sessions within the past three months (β = 0.216, p < .05) experienced greater physical symptom distress. Additionally, those who experienced greater physical symptom distress perceived lower personal control (β = -0.199, p < .05) and treatment control (β = -0.217, p < .05). Understanding the mediating effects of symptom distress on the relationship between individual differences and perceived controllability can enhance our knowledge of the mechanisms of illness acceptance, which significantly contributes to illness adaptation among women with gynecologic cancer.

ChatGPT-4o vs. oncologists in addressing endometrial cancer patient inquiries: A prospective comparative study in primary and secondary care

This prospective comparative study aimed to evaluate the performance of ChatGPT-4o in answering questions about endometrial cancer, with a focus on accuracy, empathy, and completeness in comparison to gynecologic oncologist. Additionally, it sought to explore potential differences in AI-generated responses between primary and secondary care settings, providing insights into its role at different levels of healthcare. A total of 100 questions relevant to endometrial cancer were selected and validated by specialists. Fifty questions pertained to primary care (e.g., risk factors and prevention) and fifty to secondary care (e.g., diagnosis and treatment). Both ChatGPT-4o and a gynecologic oncologist answered these questions. Responses were evaluated by two independent oncologists based on accuracy, empathy, completeness. Also readability scores and word counts are calculated. ChatGPT achieved significantly higher scores in accuracy (3.86 vs. 3.36; p < 0.001), empathy (3.47 vs. 1.66; p < 0.001), and completeness (3.00 vs. 1.97; p < 0.001) than the oncologist. Its answers, however, were much longer (403.51 vs. 25.06 words). Readability scores indicated that both ChatGPT and physician responses were similarly challenging to comprehend, requiring a high level of literacy. ChatGPT-4o demonstrated superior accuracy, empathy, and completeness in addressing questions about endometrial cancer compared to gynecologic oncologist. However, its lengthy responses could be overwhelming for patients. These findings suggest AI tools like ChatGPT-4o could support oncology nurses in delivering accurate patient education and empathetic communication, enhancing supportive care in endometrial cancer management. Future efforts should balance detail with clarity, enhancing AI's practical applicability in healthcare.

Publisher

Elsevier BV

ISSN

1462-3889