Actas Españolas de Psiquiatría

Analysis of the Development Trajectory and Influencing Factors of Depression in Patients With Cervical Cancer During Concurrent Chemoradiotherapy

Background: This study aims to analyse the developmental trajectory of depression in patients undergoing concurrent chemoradiotherapy (CCRT) for cervical cancer and its influencing factors. Methods: A retrospective analysis of clinical data was performed on 160 patients with cervical cancer who received CCRT at our hospital between July 2023 and June 2025. Individuals with depression were assigned to the depressed group, whereas those without depression were assigned to the non-depressed group. Employing latent class growth modelling to identify depression trajectories in cervical cancer patients undergoing CCRT. The factors influencing the latent classes of depression trajectories in patients were analysed through logistic regression. Results: The depressed group had higher rates of household monthly income per capita of less than 5000 RMB (1 USD = 7.1 RMB), stage III/IV tumour stage and avoidance/submission coping methods than the non depressed group (p = 0.001, 0.030, < 0.001) and had lower Multidimensional Scale of Perceived Social Support (MSPSS) scores (p = 0.001). Three distinct depression trajectories were identified: a low-level stable group (n = 31), a moderate-level increasing group (n = 54) and a high-level decreasing group (n = 29). The logistic regression analysis results indicated that patients with a household income per capita below 5000 RMB, stage III/IV tumour stage, avoidance/submission coping style and lower MSPSS scores exhibited a higher likelihood of entering the medium-level rising group and the high-level declining group compared to the other group (p < 0.05). Conclusions: Depression in patients with cervical cancer exhibits three distinct developmental trajectories. Household income per capita, tumour stage, coping style and MSPSS score may influence these trajectories. Thus, prompt intervention targeting these potential influencing factors is essential for managing the progression of depression.

Quality of Life and Anxiety Status of Patients with Ovarian Tumor Undergoing Enhanced Recovery after Surgery

Background: This study aimed to explore the quality of life and anxiety status of patients with ovarian tumor undergoing enhanced recovery after surgery (ERAS).    Methods: This article retrospectively analyzed the clinical data of 300 patients with ovarian tumor admitted in the First Affiliated Hospital of Hebei North University. The patients were divided into two groups according to the perioperative management methods. A total of 156 patients who received traditional perioperative management were included in the control group, and the ERAS group included 144 patients who received traditional perioperative management combined with ERAS management. Quality of life questionnaire-C30 (QLQ-C30) and self-rating anxiety scale (SAS) were used to compare the postoperative quality of life and anxiety status.    Results: The ERAS group showed significantly shorter first feeding time (p < 0.001), exhaust time (p < 0.001) and defecation time (p = 0.002), infusion time (p = 0.026), and hospitalization time (p < 0.001) than the control group. Inter-group comparison showed no significant difference in QLQ-C30 scores in terms of physical (p = 0.345), role (p = 0.509), emotional (p = 0.235), cognitive (p = 0.462), and social functions (p = 0.645) before surgery. The scores of physical, role, emotional, cognitive, and social functions in the ERAS group were significantly higher than the control group after surgery (p < 0.001). There was no significant difference in preoperative anxiety scores between the two groups (p = 0.056). The postoperative anxiety score of the ERAS group was significantly lower than that of the control group (p = 0.002).  Conclusions: ERAS could alleviate the postoperative negative emotions such as anxiety, promote the physical and mental health and improve the quality of life of patients with ovarian tumor.