Uterine Tumor Resembling Ovarian Sex Cord Tumors (UTROSCT): Two
Case Reports of the Rare Uterine Neoplasm with Literature Review
Introduction:
Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare
neoplasms with unknown etiology. This type of tumor has low malignant potential and mostly manifests
as a benign clinical course.
Materials and Methods:
This article analyzes the case data, clinical manifestations, and histopathological
characteristics of two cases of UTROSCT, and reviews the relevant literature. The diagnosis of
UTROSCT is mainly based on histopathological examination. The histological characteristics of granulosa
and Sertoli cell tumours are similar to the ovary under the microscope. These cases' clinical and
radiological (MRI) findings have also been discussed.
Results:
The sex cord components are mixed in different proportions. The immunohistochemistry is
diverse and can express sex cord markers together with both epithelial and smooth muscle markers.
Both two cases revealed the signs of intratumoral cystic degeneration, intratumoral hemorrhage, and
necrosis under MRI. These MRI features were helpful to prompt UTROSCT, which is histologically
similar to granular cell tumors and is conducive to the differential diagnosis.
Conclusion:
The current recommended treatment is total hysterectomy, but its biological behavior is
not yet clear, and long-term follow-up is needed.
