Yee Sing Lin

Evaluating the Cytomorphologic Features of Cervical Adenosquamous Carcinoma

ABSTRACTPrior studies suggest that adenosquamous histology confers a poorer prognosis when compared with other histologic subtypes of carcinoma in the cervix. However, there is limited literature describing the cytologic features of this entity. Herein we report on a series of adenosquamous carcinomas of the uterine cervix diagnosed within our institution to evaluate the range of cytomorphologic features and integrate clinical and genotypic data.

Myoepithelioma‐like tumour of the vulval region: A case report

AbstractMyoepithelioma‐like tumours of the vulvar region (MELTVR) are a newly described group of spindle cell neoplasm. Morphologically, they consist of epithelioid to spindled cells in a myxoid to collagenous stroma and can resemble epithelioid sarcomas, myoepithelial carcinomas or extraskeletal myxoid chondrosarcomas. However, they have a distinct pattern of immunohistochemical staining characterised by positivity for EMA, ER, PR and negativity for cytokeratin, GFAP and S100. Nuclear staining for INI‐1 is lost. In addition, they lack the characteristic gene arrangements of these other lesions. MELTVR can recur locally when incompletely excised, however, do not appear to metastasize. We report a case of a MELTVR in a 49‐year‐old woman arising in the right mons pubis.