Investigator

Wei Shen

Jiangsu University of Science and Technology, School of Environmental and Chemical Engineering

WSWei Shen
Papers(2)
Highly Sensitive Dete…Surgical Management o…
Collaborators(2)
Hian Kee LeeSheng Tang
Institutions(2)
Jiangsu University Of…Duke Nus Medical Scho…

Papers

Surgical Management of Uterine Fibroids: A Large Retrospective Study

To analyze trends in surgical management of uterine fibroids and identify factors influencing surgical decisions among Chinese women over the past decade. Retrospective cohort study. Four campuses of Tongji Hospital, a tertiary care center in Wuhan, China. Of the 104,430 women screened, 13,344 were diagnosed with uterine fibroids and underwent surgical treatment between 2013 and 2022. Exclusion criteria were concurrent adenomyosis, uterine fibroids found unexpectedly during unrelated surgery (e.g., genital cancer), and pregnant women with uterine fibroids. Hysterectomy, myomectomy. Data from surgical inpatients were analyzed for annual rates of hysterectomies and myomectomies. Univariate and multivariate logistic regression models were used to identify factors associated with choice of surgery. From 2013 to 2022, hysterectomy rates decreased from 42.3% to 33.1%, with the most pronounced decline observed in the 45 to 49 age group (a 21.1 percentage point decrease), followed by the 40 to 44 age group (a 15.6 percentage point decrease). Myomectomy rates increased from 57.7% to 66.9%. Factors associated with an increased likelihood of hysterectomy included clinically significant symptoms, lower preoperative hemoglobin, multiple uterine fibroids, older age at admission, later age at menarche, and higher body mass index. Notably, among patients who underwent hysterectomies, 34.9% also had oophorectomies, compared to 1.1% in the myomectomy group. Surgical management of uterine fibroids in central China has shifted toward increased use of myomectomy over hysterectomy, particularly among women aged 40 to 49. This transition is critical given potential adverse outcomes associated with hysterectomy in premenopausal women.

60Works
2Papers
2Collaborators

Positions

2016–

Researcher

Jiangsu University of Science and Technology · School of Environmental and Chemical Engineering

Education

2016

Ph.D.

National University of Singapore · Chemistry

2011

BSc

Zhejiang University · Chemistry

Keywords
DNA detectionMicroRNA detectionSingle nucleotide polymorphismNanomaterial
Links & IDs
0000-0001-8159-5728

Scopus: 57001188100