Radiologic Assessment of Groin Lymph Nodes in Pelvic Malignancies
Metastatic involvement of groin nodes can alter radiation therapy planning for pelvic tumors. We retrospectively identified patients with vulvar, vaginal, or anal cancers who underwent Of 55 patients identified for analysis, 75 groins had pathologic evaluation resulting in 75 index groin nodes for analysis with 35 groins pathologically positive for malignancy. Logistic regression identified mean standardized-uptake-value (50% threshold) and short-axis length as the most predictive imaging metrics for metastatic nodal involvement. The probabilistic model performed better at predicting pathologic involvement compared with standard clinical interpretation on analysis (AUC 0.91, 95% CI 0.84 to 0.97 vs 0.80, 95% CI 0.71 to 0.89; p<0.01). Accuracy of
