Investigator

Ospan A. Mynbaev

The Principal Researcher · Moscow Institute of Physics and Technology, Laboratory of Human Physiology

OAMOspan A. Mynbaev
Papers(1)
Human Papillomavirus …
Collaborators(5)
Saule BalmagambetovaAndrea TinelliArip KoyshybaevElnara IsmagulovaNurgul Kereyeva
Institutions(2)
Laboratoire De Physio…West Kazakhstan Marat…

Papers

Human Papillomavirus Selected Properties and Related Cervical Cancer Prevention Issues

High-risk human papillomavirus strains are widely known to be the causative agents responsible for cervical cancer development. Aggregated damage caused by papillomaviruses solely is estimated in at least 5% of all malignancies of the human body and 16% in cancers that affect the female genital area. Enhanced understanding of the complex issue on how the high extent of carcinogenicity is eventually formed due to the infection by the Papoviridae family would contribute to enhancing current prevention strategies not only towards cervical cancer, but also other HPV associated cancers. This review article is aimed at presenting the key points in two directions: the current cervical cancer prevention and related aspects of HPV behavior. Virtually all applied technologies related to HPV diagnostics and screening programs, such as HPV tests, colposcopy-based tests (VIA/VILI), conventional and liquid-based cytology, currently available are presented. Issues of availability, advantages, and drawbacks of the screening programs, as well as vaccination strategies, are also reviewed in the article based on the analyzed sources. The current point of view regarding HPV is discussed with emphasis on the most problematic aspect of the HPV family concerning the observed increasing number of highly carcinogenic types. Present trends in HPV infection diagnostics throughout the human fluids and tissues are also reported, including the latest novelties in this field, such as HPV assay/self-sample device combinations. Besides, a brief outline of the related prevention issues in Kazakhstan, the leading country of Central Asia, is presented. Kazakhstan, as one of the post-soviet middle-income countries, may serve as an example of the current situation in those terrains, concerning the implementation of globally accepted cervical cancer prevention strategies. Along with positive achievements, such as the development of a nationwide screening program, a range of drawbacks is also analyzed and discussed.

119Works
1Papers
5Collaborators

Positions

2013–

The Principal Researcher

Moscow Institute of Physics and Technology · Laboratory of Human Physiology

2013–

The Representative

New European Surgical Academy · Country Representative

2017–

Lecturer

University of Bologna · the International Master in Minimally Invasive Gynecologic Surgery

2015–

Researcher

Pirogov Russian National Research Medical University

2013–

Professor

Peoples' Friendship University of Russia · Obstetrics, Gynecology & Reproductive Medicine

2009–

Head of Laboratory Immunology, The Principal Researcher; Head of Division; The Principal Researcher; Head of Laboratory

Moscow State University of Medicine & Dentistry named after A.I.Evdokimov · Laboratory of Immunology (2015); Laboratory Pilot Projects (2014-2015); Experimental Researches and Biomodeling division (2011-2014), Laboratory of Molecular Biology studies (2009-2013), Head, Experimental Researches & Modeling Division (2013-2014); The Principal Researcher, Laboratory of Pilot Projects (2014-2015); Head, Laboratory of Immunology (since 02. 2015

2003–

An independent researcher

International Reseach team on cancer metastasis · International Reseach team on cancer metastasis

2003–

Researcher

Ghent University

1996–

Surgeon-Consultant / Gynecologist

The Research Center for Obstetrics, Gynecology and Perinatology · Operative Gynecology

1999–

Postdoc

Katolieke University Leuven · institute of surgical technologies

1992–

Professor-assistant

South-Kazakhstan Medical Academy · Anatomy and Hystology

1985–

Researcher

Research Institute of Mother and Child Health Service of Healthcare Ministry of Kazakh SSR · Gynecology

1982–

Obstaterician and Gynecologist

Sairam Regional Medical cervises, Regional Mathernity Hospital · Obstetrics and Outpatient clinic

Education

2020

Certification

Moscow Institute of Physics and Technology

2014

Certification: Office Hysteroscopy by Stefano Bettocchi

Università degli Studi di Bari · Gynecology, Obstetrics and Neonatology

2012

Certificate/Diploma: Updates in obstetrics and gynecology

Moscow State University of Medicine and Dentistry · Obstatrics and Gynecology

2008

MSc Med.Pharm.

Ghent University · Laboratory of Experimental Cancerology, Department of Radiotherapy and Nuclear Medicine

2006

MSc Med.Pharm.

Vrije Universiteit Brussel

2002

Instructor-Researcher / Postdoc

KULeuven · Institute of Surgical Technologies

1997

ScD

The Research Center for Obstetrics, Gynecology and Perinatology and Moscow State University named after M.V.Lomonosov, Russia · Gynecology / Laboratory of Fermentative Fibrinolysis

1992

PhD

The Research Center for Obstetrics, Gynecology and Perinatology and The Russian Scientific center of Surgery, RAMS · Gynecology / Experimental Laboratory of Surgery

1987

Ob.Gyn. certification

Kiev State Institute of Postgraduate Medical Education · Obstetrics & Gynecology: Academician/Professor Leonid V Timoshenko

1982

MD / Internship

Kazakh National Medical University named after Asfendiarov · Faculty of Medicine

Country

RU

Keywords
Adhesion formationCO2-pathophysiologyCervical cancer screeningtranslational medicineHPVHSV
Links & IDs
0000-0002-9309-1938ospanmynbaev@gmail.com

Scopus: 6602811094

Researcher Id: K-5326-2013