Investigator
Princess Margaret Cancer Centre
Biomarkers in High-Grade Serous Ovarian Cancer: Context Is Everything
Summary The Oxford Classic Epithelial-to-Mesenchymal Transition (OxC-EMT) score identifies a high-risk subgroup of patients with high-grade serous carcinoma with inferior survival. This commentary discusses the evaluation of high-grade serous carcinoma biomarkers in context and the important steps in transition from a prognostic to a validated predictive biomarker to inform clinical utility. See related article by Rai et al., p. 188