Junjun Dai

Clinical Effect Analysis and Prognostic Factors of Photodynamic Therapy for Cervical Precancerous Lesions

ABSTRACTObjectiveTo evaluate the therapeutic effect of photodynamic therapy (PDT) on cervical precancerous lesions and prognostic factors.Methods173 patients diagnosed with cervical precancerous lesions and treated with PDT were included. Univariate analysis was performed on human papillomavirus (HPV) infection, patient age, number of treatments and number of medications before and after treatment, to evaluate the efficacy, adverse reactions and patient satisfaction.Results112 patients (64.5%) showed HPV clearance afrer PDT. Age ≥ 40 years was positively correlated with poor prognosis and number of treatments ≥ 6 was negatively correlated with poor prognosis. The satisfaction rate reached 94.79%, with 6 patients experiencing tolerable pain and no treatment discontinuations due to adverse reactions.ConclusionPDT is effective and safe for treating cervical precancerous lesions, with patient age and treatment frequency impacting outcomes. High patient satisfaction and tolerable adverse reactions support the application of PDT in clinical practice.