Guofen Cao

Effect of combined intravenous–inhalation anesthesia on postoperative cognitive dysfunction after laparoscopic radical resection of cervical cancer

Abstract Objective To evaluate the effect of combined intravenous–inhalation anesthesia (CIVIA) on postoperative cognitive dysfunction (POCD) after laparoscopic radical resection of cervical cancer. Methods By using a predefined standardized study protocol, we conducted a systematic review of randomized controlled trials (RCTs) with meta-analysis, searching the following data bases: PubMed, Embase, Web of Science, and Cochrane Library. Results This systematic review evaluated the effect of CIVIA on POCD after laparoscopic radical resection of cervical cancer. Conclusion This systematic review provided up-to-date evidence to evaluate the effect of CIVIA on POCD after laparoscopic radical resection of cervical cancer. OSF Registration number: DOI 10.17605/OSF.IO/82FNA.